SCHEMBL7781829

SCHEMBL7781829

CC(C)NC(=O)C(C)CN(C)C.COC(=O)C(C)CN(C)C

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
THRB P10828 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TSHR P16473 1/20 0.33
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
CA9 Q16790 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GAA P10253 1/20 0.31
MME P08473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7129808 0.89 MEN1 (0.34) ALDH1A1TSHRCA12CA1CA2
SCHEMBL29531381 0.87 SMN1; SMN2 (0.39) ALDH1A1HSD17B10TSHRCA12CA1
SCHEMBL7136164 0.87 SMN1; SMN2 (0.39) ALDH1A1HSD17B10TSHRCA12CA1
SCHEMBL29531261 0.87 SMN1; SMN2 (0.39) ALDH1A1HSD17B10TSHRCA12CA1
SCHEMBL27721767 0.72
SCHEMBL10947530 0.71 TSHR (0.43) ALDH1A1THRBCYP2C9CYP2C19HSD17B10
SCHEMBL8747892 0.71 L3MBTL1 (0.41) ALDH1A1THRBCYP2C9CYP2C19HSD17B10
SCHEMBL24723658 0.70 CHRNB2 (0.34) ALDH1A1CYP2C19HSD17B10TSHRGAA
SCHEMBL15314139 0.70 CHRNB2 (0.34) ALDH1A1CYP2C19HSD17B10TSHRGAA
SCHEMBL31462139 0.70 CHRNB2 (0.37) ALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140797-A1 PRODUCTION OF ACRYLIC MONOMERS Ciba Specialty Chemicals Water Treatments Limited (GB) 2001-10-10 EP disclosed
WO-2000041996-A1 PRODUCTION OF ACRYLIC MONOMERS CIBA SPECIALTY CHEMICALS WATER TREATMENTS LIMITED (GB) 2000-07-20 WO disclosed