SCHEMBL7781980

SCHEMBL7781980

CSCCC(N)C(=O)Oc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MARS1 P56192 7/20 0.42
TDP1 Q9NUW8 1/20 0.41
METAP2 P50579 2/20 0.40
METAP1 P53582 2/20 0.40
CTSC P53634 1/20 0.40
ELANE P08246 1/20 0.40
POLB P06746 1/20 0.39
MME P08473 1/20 0.38
ANPEP P15144 1/20 0.38
BCL2 P10415 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7546444 1.00 ATM (0.43) ATML3MBTL1MARS1TDP1METAP2
Hydrochloric Acid SCHEMBL28125798 0.98 ATM (0.42) ATML3MBTL1MARS1TDP1METAP2
SCHEMBL12229268 0.86 LMNA (0.43) MARS1
SCHEMBL12229225 0.86 LMNA (0.43) MARS1
SCHEMBL19283982 0.84 LMNA (0.49) L3MBTL1MARS1TDP1POLB
SCHEMBL180586 0.83 PTPN1 (0.48) TDP1
SCHEMBL23129826 0.82 MARS1 (0.47) ATML3MBTL1MARS1TDP1
Arginine SCHEMBL19283975 0.82 FNTA (0.41) MARS1CTSC
SCHEMBL15993776 0.81 TDP1 (0.42) ATML3MBTL1MARS1TDP1CTSC
SCHEMBL1133955 0.80 KMT2A (0.53) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1135398-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION Monsanto Technology LLC (US) 2001-09-26 EP disclosed
US-6218563-B1 Cyanophosphonamides and method for preparation MONSANTO COMPANY 2001-04-17 US disclosed
WO-2000032611-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION MONSANTO TECHNOLOGY LLC (US) 2000-06-08 WO disclosed
US-4304715-A Enkephalin analogues HUDSON DEREK 1981-12-08 US disclosed
US-RE30731-E Enkephalin analogues Hudson, Derek (GB) 1981-09-01 US disclosed
US-4198398-A Enkephalin analogues HUDSON DEREK (GB) 1980-04-15 US disclosed