Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.72 |
| ▸ | NPC1 | O15118 | 8/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | CASP3 | P42574 | 3/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787088 | 0.88 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL22585367 | 0.86 | NPC1 (0.78) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31680576 | 0.86 | RAB9A (0.81) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL4724997 | 0.84 | SMN1; SMN2 (1.00) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL30684671 | 0.84 | CA12 (0.59) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL571295 | 0.84 | CA12 (0.59) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL10943445 | 0.84 | RAB9A (0.88) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL5879030 | 0.84 | RAB9A (0.88) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL2824645 | 0.83 | AR (0.67) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL10939388 | 0.83 | SMN1; SMN2 (0.91) | RAB9ANPC1SMN1; SMN2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251917-B1 | Benzamidoaldehydes and their use as cysteine protease inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |