⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29407414 | 0.87 | FAAH (0.50) | — | |
| SCHEMBL28356920 | 0.84 | — | — | |
| SCHEMBL2186533 | 0.84 | GAA (0.53) | — | |
| SCHEMBL18607077 | 0.82 | FAAH (0.58) | — | |
| SCHEMBL27653265 | 0.82 | — | — | |
| SCHEMBL622441 | 0.81 | — | — | |
| SCHEMBL8896628 | 0.79 | CNR1 (0.53) | — | |
| SCHEMBL4103969 | 0.79 | SELP (0.56) | — | |
| SCHEMBL788322 | 0.79 | — | — | |
| SCHEMBL27765123 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251898-B1 | Medical use of fluorenone derivatives for treating and preventing brain and spinal injury | QUESTCOR PHARMACEUTICALS, INC. | 2001-06-26 | — | — | US | disclosed |
| WO-2001014334-A1 | FLUORENONE COMPOUNDS WITH MODIFIED 7-POSITION SUBSTITUENTS FOR TREATING AND PREVENTING BRAIN AND SPINAL INJURY | QUESTCOR PHARMACEUTICALS, INC. (US) | 2001-03-01 | — | — | WO | disclosed |