Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 7/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776855 | 0.75 | PARP1 (0.51) | CYP1A2HIF1APARP1PARP15PARP3 | |
| SCHEMBL10150407 | 0.74 | PARP1 (0.59) | CYP1A2HIF1APARP1PARP15PARP3 | |
| SCHEMBL7782092 | 0.72 | KMT2A (0.54) | CYP1A2PARP1KDM4EALDH1A1MAPT | |
| SCHEMBL3122203 | 0.71 | PARP1 (0.59) | CYP1A2HIF1APARP1PARP15PARP3 | |
| SCHEMBL18711836 | 0.66 | PARP1 (0.62) | CYP1A2HIF1APARP1PARP15PARP3 | |
| SCHEMBL5555023 | 0.63 | L3MBTL1 (0.51) | CYP1A2HIF1APARP1PARP15PARP3 | |
| SCHEMBL5253471 | 0.63 | PARP1 (0.38) | CYP1A2HIF1APARP1PARP15PARP3 | |
| SCHEMBL18711684 | 0.62 | PARP1 (0.49) | CYP1A2HIF1APARP1PARP15PARP3 | |
| SCHEMBL10287003 | 0.61 | KDM4E (0.33) | KDM4EALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL12602225 | 0.61 | ACHE (0.48) | CYP1A2PARP1PARP15PARP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142881-A1 | POLY(ADP-RIBOSE) POLYMERASE INHIBITORS CONSISTING OF PYRIMIDINE DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |