SCHEMBL7782064

SCHEMBL7782064

O=C(c1[c]cccc1C(=O)c1c(Cl)cccc1Cl)c1c(Cl)cccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
TSHR P16473 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
PBRM1 Q86U86 1/20 0.37
GABRP O00591 2/20 0.37
GABRD O14764 2/20 0.37
GABRA1 P14867 2/20 0.37
GABRB1 P18505 2/20 0.37
GABRG2 P18507 2/20 0.37
GABRB3 P28472 2/20 0.37
GABRA5 P31644 2/20 0.37
GABRA3 P34903 2/20 0.37
GABRA2 P47869 2/20 0.37
GABRB2 P47870 2/20 0.37
GABRA4 P48169 2/20 0.37
GABRE P78334 2/20 0.37
GABRA6 Q16445 2/20 0.37
GABRG1 Q8N1C3 2/20 0.37
GABRG3 Q99928 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13370382 0.76 CA12 (0.47) NPC1
SCHEMBL2305379 0.73 KMT2A (0.39) ALDH1A1POLBLMNAGAAHPGD
SCHEMBL9726458 0.72 ALDH1A1 (0.67) ALDH1A1TSHRCES2CES1PBRM1
SCHEMBL11292197 0.70 RECQL (0.51) ALDH1A1TSHRCES2CES1CYP1A2
SCHEMBL1181086 0.70 ALDH1A1 (0.45) ALDH1A1TSHRCES2CES1POLB
SCHEMBL611462 0.69 MEN1 (0.54) ALDH1A1CES2CES1RORCCYP1A2
SCHEMBL1451727 0.69 AKR1C3 (0.53) ALDH1A1CYP2C9LMNAGAAGLA
SCHEMBL10626896 0.69 ALDH1A1 (0.42) ALDH1A1TSHRCES2CES1PBRM1
SCHEMBL10438612 0.68 ITGB1 (0.35) ALDH1A1GABRPGABRDGABRA1GABRB1
SCHEMBL7179689 0.68 ALDH1A1 (0.45) ALDH1A1TSHRCES2CES1PBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1141952-A1 UV-RADIATION-HARDENABLE BINDER COMPOSITION FOR MAGNETIC RECORDING MEDIA AND PHOTOINITIATOR MIXTURE EMTEC Magnetics GmbH (DE) 2001-10-10 EP disclosed
WO-2000028531-A1 UV-RADIATION-HARDENABLE BINDER COMPOSITION FOR MAGNETIC RECORDING MEDIA AND PHOTOINITIATOR MIXTURE EMTEC MAGNETICS GMBH (DE) 2000-05-18 WO disclosed