SCHEMBL7782116

SCHEMBL7782116

O=[N+]([O-])c1ccccc1NN(c1ccccc1)[N+](=O)[O-]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 4/20 0.53
L3MBTL1 Q9Y468 4/20 0.53
ALDH1A1 P00352 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
CASP7 P55210 1/20 0.53
KAT2B Q92831 2/20 0.46
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
RAB9A P51151 5/20 0.45
NPC1 O15118 3/20 0.45
MAPT P10636 8/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
GAA P10253 4/20 0.44
PKM P14618 1/20 0.44
POLB P06746 1/20 0.43
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KCNMA1 Q12791 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265122 0.83 MAPK1 (0.56) MAPK1L3MBTL1ALDH1A1TDP1CASP7
SCHEMBL5767631 0.79 RAB9A (0.57) MAPK1ALDH1A1MEN1KMT2ARAB9A
SCHEMBL9302982 0.73 MEN1 (0.56) MAPK1L3MBTL1ALDH1A1TDP1MEN1
SCHEMBL397773 0.72 MAPK1 (0.77) MAPK1L3MBTL1ALDH1A1TDP1CASP7
SCHEMBL27970010 0.71 MEN1 (0.48) MAPK1L3MBTL1ALDH1A1TDP1CASP7
Benzene SCHEMBL28395815 0.71 MAPK1 (0.63) MAPK1L3MBTL1ALDH1A1TDP1CASP7
SCHEMBL9616082 0.71 ALDH1A1 (0.42) MAPK1L3MBTL1ALDH1A1TDP1MEN1
SCHEMBL38002 0.71 ALDH1A1 (0.42) MAPK1L3MBTL1ALDH1A1TDP1CASP7
SCHEMBL27602464 0.70 ALDH1A1 (0.67) MAPK1L3MBTL1ALDH1A1TDP1CASP7
SCHEMBL31333098 0.69 TDP1 (1.00) MAPK1L3MBTL1ALDH1A1TDP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107661752-A A kind of graphene oxide/prussian blue nano particulate composite solid phase micro extraction probe and its preparation method and application 中山大学 2018-02-06 CN disclosed
EP-1135398-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION Monsanto Technology LLC (US) 2001-09-26 EP disclosed
WO-2000032611-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION MONSANTO TECHNOLOGY LLC (US) 2000-06-08 WO disclosed