Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782165 | 1.00 | L3MBTL1 (0.44) | L3MBTL1ATMSMN1; SMN2PKMCYP1A2 | |
| Sulfuric Acid SCHEMBL11049283 | 0.94 | L3MBTL1 (0.40) | L3MBTL1ATMSMN1; SMN2PKMCYP1A2 | |
| SCHEMBL7782886 | 0.87 | ATM (0.45) | L3MBTL1ATMSMN1; SMN2PKMSLC1A3 | |
| SCHEMBL7782885 | 0.87 | ATM (0.45) | L3MBTL1ATMSMN1; SMN2PKMSLC1A3 | |
| SCHEMBL7709512 | 0.86 | ATM (0.44) | L3MBTL1ATMPKMSLC1A3ALDH1A1 | |
| SCHEMBL1459632 | 0.83 | KMT2A (0.48) | L3MBTL1ATMSMN1; SMN2PKMCYP1A2 | |
| SCHEMBL7780251 | 0.83 | KMT2A (0.48) | L3MBTL1ATMSMN1; SMN2PKMCYP1A2 | |
| SCHEMBL24530374 | 0.81 | ATM (0.46) | L3MBTL1ATMPKMSLC1A3ELANE | |
| SCHEMBL2564139 | 0.81 | ATM (0.46) | L3MBTL1ATMSMN1; SMN2PKMCYP1A2 | |
| SCHEMBL16086931 | 0.81 | ATM (0.46) | L3MBTL1ATMSMN1; SMN2PKMCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368084-A | Biaryl kinase inhibitors | 百时美施贵宝公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-108290843-A | Biaryl based kinase inhibitors | 百时美施贵宝公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-1667113-A | Process for making tuber of elevated gastrodia wine | LIU JIANHUA (CN) | 2005-09-14 | — | — | CN | disclosed |
| EP-1135398-A1 | CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION | Monsanto Technology LLC (US) | 2001-09-26 | — | — | EP | disclosed |
| US-6218563-B1 | Cyanophosphonamides and method for preparation | MONSANTO COMPANY | 2001-04-17 | — | — | US | disclosed |
| WO-2000032611-A1 | CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION | MONSANTO TECHNOLOGY LLC (US) | 2000-06-08 | — | — | WO | disclosed |