Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782182 | 1.00 | MAOA (0.32) | MAOAMAOBSPHK2SPHK1ALOX5 | |
| SCHEMBL7781478 | 0.92 | THRA (0.34) | MAOAMAOBSPHK2SPHK1THRA | |
| SCHEMBL7781473 | 0.92 | THRA (0.34) | MAOAMAOBSPHK2SPHK1THRA | |
| SCHEMBL7781745 | 0.91 | THRA (0.36) | SPHK2SPHK1THRATHRB | |
| SCHEMBL7781743 | 0.91 | THRA (0.36) | SPHK2SPHK1THRATHRB | |
| SCHEMBL10640463 | 0.87 | NISCH (0.35) | MAOAMAOBSPHK2SPHK1ALOX5 | |
| SCHEMBL7779343 | 0.84 | KDM1A (0.31) | — | |
| SCHEMBL7774325 | 0.84 | MAOA (0.33) | MAOAMAOBSPHK2SPHK1ALOX5 | |
| SCHEMBL7779349 | 0.84 | KDM1A (0.31) | — | |
| SCHEMBL7774319 | 0.84 | MAOA (0.33) | MAOAMAOBSPHK2SPHK1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732330-B1 | Di-1,3-dioxane derivatives useful as liquid crystals | ROLIC AG (CH) | 2001-09-12 | — | — | EP | disclosed |
| US-5667721-A | Liquid crystalline di-1,3-dioxane derivatives | ROLIC AG (CH) | 1997-09-16 | — | — | US | disclosed |
| EP-0732330-A1 | Di-1,3-dioxane derivatives useful as liquid crystals | F. HOFFMANN-LA ROCHE AG (CH) | 1996-09-18 | — | — | EP | disclosed |