SCHEMBL778222

SCHEMBL778222

CC1(C)CC1(C(=O)O)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.45
MAPK1 P28482 2/20 0.35
NFKB1 P19838 2/20 0.35
CYP2C19 P33261 2/20 0.35
TP53 P04637 1/20 0.35
THPO P40225 1/20 0.35
STAT6 P42226 1/20 0.35
HIF1A Q16665 1/20 0.35
NPC1 O15118 1/20 0.35
GMNN O75496 1/20 0.35
LMNA P02545 1/20 0.35
MTOR P42345 1/20 0.35
RAB9A P51151 1/20 0.35
BLM P54132 1/20 0.35
PMP22 Q01453 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
APLNR P35414 1/20 0.33
PKM P14618 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18261822 0.85 FFAR3 (0.39) FFAR3MAPK1NFKB1CYP2C19TP53
SCHEMBL11275666 0.85 FFAR3 (0.39) FFAR3MAPK1NFKB1CYP2C19TP53
SCHEMBL27596437 0.83 PKM (0.42) FFAR3MAPK1NFKB1CYP2C19TP53
SCHEMBL2380339 0.83 FFAR3 (0.38) FFAR3MAPK1NFKB1CYP2C19TP53
SCHEMBL11757525 0.81 FFAR3 (0.36) FFAR3
SCHEMBL27541216 0.79 MEN1 (0.40) FFAR3LMNANPSR1
SCHEMBL3097649 0.78 FFAR3 (0.43) FFAR3MAPK1NFKB1CYP2C19TP53
SCHEMBL11229706 0.75 FFAR3 (0.32) FFAR3
SCHEMBL18438824 0.75 FFAR3 (0.48) FFAR3MAPK1NFKB1CYP2C19TP53
Bicarbonate SCHEMBL2943876 0.74 FFAR3 (0.44) FFAR3MAPK1NFKB1CYP2C19TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011101857-A2 MULTIFUNCTIONAL TEXTILE KHANDELWAL, SANJEEV (IN) 2011-08-25 WO claimed
JP-57002272-A None JP disclosed
CN-113164433-B Oily moisturizer and external composition for skin containing same 日清奥利友集团株式会社 2024-07-09 CN disclosed
EP-3329918-B1 C-MET MODULATORS AND METHODS OF USE EXELIXIS INC (US) 2022-05-25 EP disclosed
US-11124482-B2 C-met modulators and methods of use EXELIXIS, INC. (US) 2021-09-21 US disclosed
US-20210253530-A9 C-MET MODULATORS AND METHODS OF USE EXELIXIS, INC. 2021-08-19 US disclosed
CN-113164433-A Oily moisturizer and skin external composition comprising same 日清奥利友集团株式会社 2021-07-23 CN disclosed
CN-113164432-A Oily moisturizer and skin external composition comprising same 日清奥利友集团株式会社 2021-07-23 CN disclosed
US-20200331860-A1 C-Met Modulators and Methods of Use EXELIXIS INC (US) 2020-10-22 US disclosed
EP-3329918-A2 C-MET MODULATORS AND METHODS OF USE Exelixis, Inc. (US) 2018-06-06 EP disclosed
EP-1268581-A2 STABLE INITIATOR SYSTEM Johnson & Johnson Vision Care, Inc. (US) 2003-01-02 EP disclosed
US-6414049-B1 SILICONE, ACYLPHOSPHINE PROMOTER, ACID MIXTURE JOHNSON & JOHNSON VISION CARE, INC. 2002-07-02 US disclosed
WO-2001070824-A2 STABLE INITIATOR SYSTEM JOHNSON & JOHNSON VISION CARE, INC. (US) 2001-09-27 WO disclosed
EP-1018870-A1 SURFACTANTS FOR USE IN AGRICULTURAL FORMULATIONS HENKEL CORPORATION (US) 2000-07-19 EP disclosed
WO-1999003343-A1 SURFACTANTS FOR USE IN AGRICULTURAL FORMULATIONS HENKEL CORPORATION (US) 1999-01-28 WO disclosed
US-5075488-A Fungicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-24 US disclosed
EP-0128006-B1 A SOIL-DISEASE-CONTROLLING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-09-18 EP disclosed
US-4709052-A FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-11-24 US disclosed
EP-0128006-A2 A soil-disease-controlling agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-12-12 EP disclosed
JP-S572272-A PREPARATION OF N-PHENYLCYCLOPROPANEDICARBOXYLIC ACID IMIDE DERIVATIVE SUMITOMO CHEM CO LTD 1982-01-07 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200331860-A1 C-Met Modulators and Methods of Use FLT4, FLT1, MET FFAR3 1156/4885MAPK1 521/4885NFKB1 1958/4885
US-20210253530-A9 C-MET MODULATORS AND METHODS OF USE FLT4, FLT1, MET FFAR3 1156/4885MAPK1 521/4885NFKB1 1958/4885
US-11124482-B2 C-met modulators and methods of use FLT4, FLT1, MET FFAR3 1156/4885MAPK1 521/4885NFKB1 1958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.