Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11472131 | 0.98 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL11472132 | 0.98 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL11384060 | 0.86 | MEN1 (0.57) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL11379799 | 0.86 | MEN1 (0.57) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL7778947 | 0.84 | ALDH1A1 (0.48) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL7782342 | 0.84 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL11485620 | 0.83 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL11485616 | 0.83 | RAB9A (0.49) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL11480601 | 0.81 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL11480596 | 0.81 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949247-B1 | Process for the preparation of piperidinylidene derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2001-09-12 | — | — | EP | claimed |
| US-6008358-A | Process for the preparation of piperidinylidene derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-12-28 | — | — | US | claimed |
| EP-0949247-A1 | Process for the preparation of piperidinylidene derivatives | Takasago International Corporation (JP) | 1999-10-13 | — | — | EP | claimed |
| EP-0949247-B1 | Process for the preparation of piperidinylidene derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-6008358-A | Process for the preparation of piperidinylidene derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-12-28 | — | — | US | disclosed |
| US-6008358-A | Process for the preparation of piperidinylidene derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0949247-A1 | Process for the preparation of piperidinylidene derivatives | Takasago International Corporation (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0949247-A1 | Process for the preparation of piperidinylidene derivatives | Takasago International Corporation (JP) | 1999-10-13 | — | — | EP | disclosed |