Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775551 | 0.89 | RECQL (0.47) | HTR2AACHEBACE1MALT1RECQL | |
| SCHEMBL7779988 | 0.82 | HTR6 (0.49) | HTR2AACHEBACE1SMN1; SMN2BCHE | |
| SCHEMBL7068759 | 0.80 | HPGD (0.48) | SMN1; SMN2 | |
| SCHEMBL13005299 | 0.78 | ACHE (0.57) | ACHEBACE1BCHETACR1 | |
| SCHEMBL13676573 | 0.78 | ACHE (0.57) | ACHEBACE1BCHETACR1 | |
| SCHEMBL13676574 | 0.78 | ACHE (0.57) | ACHEBACE1BCHETACR1 | |
| SCHEMBL7775686 | 0.76 | ACHE (0.54) | HTR2AACHEBACE1ABL1RIN1 | |
| SCHEMBL537414 | 0.76 | ACHE (0.54) | ACHEBACE1BCHETACR1 | |
| SCHEMBL2676077 | 0.76 | ACHE (0.54) | ACHEBACE1BCHETACR1 | |
| SCHEMBL2676079 | 0.76 | ACHE (0.54) | ACHEBACE1BCHETACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855390-B1 | A process for producing optically active pyrrolidine derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2001-10-04 | — | — | EP | claimed |