Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930298 | 1.00 | NPC1 (0.43) | NPC1PPM1BCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL7187471 | 1.00 | NPC1 (0.43) | NPC1PPM1BCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL5213230 | 1.00 | NPC1 (0.43) | NPC1PPM1BCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL7187461 | 0.91 | PPM1B (0.44) | NPC1PPM1BCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL5426737 | 0.88 | NPC1 (0.44) | NPC1PPM1BCHRNB2CHRNA5CHRNA7 | |
| Benzoic Acid 2,3-Epoxypropyl Ester SCHEMBL21245419 | 0.81 | NPC1 (0.56) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| Benzoic Acid 2,3-Epoxypropyl Ester SCHEMBL14570069 | 0.81 | NPC1 (0.56) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| Benzoic Acid 2,3-Epoxypropyl Ester SCHEMBL133986 | 0.81 | NPC1 (0.56) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| Benzoic Acid 2,3-Epoxypropyl Ester SCHEMBL5604855 | 0.81 | NPC1 (0.56) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL20869808 | 0.81 | CHRNB2 (0.46) | NPC1PPM1BCHRNB2CHRNA5CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1151133-A1 | STEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES | McGILL UNIVERSITY (CA) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000047759-A1 | STEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES | SHIRE BIOCHEM INC. (CA) | 2000-08-17 | — | — | WO | disclosed |