Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PPM1B | O75688 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782571 | 1.00 | NPC1 (0.43) | NPC1PPM1BCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL1930298 | 1.00 | NPC1 (0.43) | NPC1PPM1BCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL7187471 | 1.00 | NPC1 (0.43) | NPC1PPM1BCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL7187461 | 0.91 | PPM1B (0.44) | NPC1PPM1BCHRNB2CHRNA5CHRNA7 | |
| SCHEMBL5426737 | 0.88 | NPC1 (0.44) | NPC1PPM1BCHRNB2CHRNA5CHRNA7 | |
| Benzoic Acid 2,3-Epoxypropyl Ester SCHEMBL21245419 | 0.81 | NPC1 (0.56) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| Benzoic Acid 2,3-Epoxypropyl Ester SCHEMBL14570069 | 0.81 | NPC1 (0.56) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| Benzoic Acid 2,3-Epoxypropyl Ester SCHEMBL133986 | 0.81 | NPC1 (0.56) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| Benzoic Acid 2,3-Epoxypropyl Ester SCHEMBL5604855 | 0.81 | NPC1 (0.56) | NPC1CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL20869808 | 0.81 | CHRNB2 (0.46) | NPC1PPM1BCHRNB2CHRNA5CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265890-B1 | STEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES | SHIRE BIOCHEM INC (CA) | 2007-04-18 | — | — | EP | disclosed |
| US-6743910-B2 | VIRICIDES, ANTICANCER AGENTS | BIOCHEM PHARMA, INC. (CA) | 2004-06-01 | — | — | US | disclosed |
| US-20030187262-A1 | Stereoselective synthesis of nucleoside analogues | BIOCHEM PHARMA INC. (CA) | 2003-10-02 | — | — | US | disclosed |
| US-6541625-B2 | Stereoselectively hydrolyzing an anomeric mixture of 2-benzoyloxydioxolanecarboxylate with an enzyme; separating product; replacing carboxylate by reaction with a purine or pyrimidinyl derivative | BIOCHEM PHARMA, INC. (CA) | 2003-04-01 | — | — | US | disclosed |
| EP-1265890-A1 | STEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES | Shire Biochem Inc. (CA) | 2002-12-18 | — | — | EP | disclosed |
| US-20020006635-A1 | Stereoselective synthesis of nucleoside analogues | BIOCHEM PHARMA, INC. (CA) | 2002-01-17 | — | — | US | disclosed |
| EP-1151133-A1 | STEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES | McGILL UNIVERSITY (CA) | 2001-11-07 | — | — | EP | disclosed |
| WO-2001058894-A1 | STEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES | SHIRE BIOCHEM INC. (CA) | 2001-08-16 | — | — | WO | disclosed |
| WO-2000047759-A1 | STEREOSELECTIVE SYNTHESIS OF NUCLEOSIDE ANALOGUES | SHIRE BIOCHEM INC. (CA) | 2000-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187262-A1 | Stereoselective synthesis of nucleoside analogues | PNP, CTRC, CPN1 | NPC1 3102/4885PPM1B 450/4885CHRNB2 1905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.