Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD5 | P21918 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865718 | 0.91 | PDE2A (0.42) | ADRB2SLC6A4AKR1C3AKR1C2HTR2A | |
| Ammonia Solution, Strong SCHEMBL7569458 | 0.89 | IDO1 (0.40) | ADRB2SLC6A3SLC6A4HTR1ADRD2 | |
| SCHEMBL6819226 | 0.87 | ADRB2 (0.45) | ADRB2AKR1C3AKR1C2PDE2AIDO1 | |
| SCHEMBL13877352 | 0.87 | ADRB2 (0.45) | ADRB2AKR1C3AKR1C2PDE2AIDO1 | |
| SCHEMBL7782593 | 0.86 | IDO1 (0.42) | ADRB2SLC6A3IDO1OPRL1 | |
| Hydrochloric Acid SCHEMBL4229200 | 0.85 | IDO1 (0.46) | ADRB2AKR1C3AKR1C2PDE2AIDO1 | |
| Hydrochloric Acid SCHEMBL27798912 | 0.85 | IDO1 (0.46) | ADRB2AKR1C3AKR1C2PDE2AIDO1 | |
| SCHEMBL5019023 | 0.85 | PDE2A (0.43) | ADRB2SLC6A4AKR1C3AKR1C2HTR2A | |
| SCHEMBL296445 | 0.85 | PDE2A (0.43) | ADRB2SLC6A4AKR1C3AKR1C2HTR2A | |
| SCHEMBL2399327 | 0.85 | PDE2A (0.43) | ADRB2SLC6A4AKR1C3AKR1C2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137632-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1137633-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034238-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000034237-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |