Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TK1 | P04183 | 2/20 | 0.34 |
| ▸ | TK2 | O00142 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PAX3 | P23760 | 1/20 | 0.32 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7782820 | 1.00 | KDM4E (0.41) | KDM4ETK1TK2NOS1POLA1 | |
| SCHEMBL3955597 | 0.82 | KDM4E (0.39) | KDM4ELMNASMN1; SMN2PAX3FOXO1 | |
| SCHEMBL22639182 | 0.80 | KDM4E (0.42) | KDM4ETK1TK2NOS1POLA1 | |
| SCHEMBL7053282 | 0.79 | SMN1; SMN2 (0.40) | KDM4ELMNASMN1; SMN2PAX3FOXO1 | |
| SCHEMBL26298314 | 0.76 | KDM4E (0.49) | KDM4ETK1TK2POLA1 | |
| SCHEMBL25507075 | 0.71 | KDM4E (0.72) | KDM4EPOLA1LMNASMN1; SMN2 | |
| SCHEMBL10068104 | 0.71 | KDM4E (0.72) | KDM4EPOLA1LMNASMN1; SMN2 | |
| SCHEMBL20346237 | 0.71 | KDM4E (0.72) | KDM4EPOLA1LMNASMN1; SMN2 | |
| SCHEMBL264545 | 0.71 | KDM4E (0.72) | KDM4EPOLA1LMNASMN1; SMN2 | |
| SCHEMBL12714741 | 0.71 | KDM4E (0.72) | KDM4EPOLA1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1138688-A1 | N8- and C8- linked purine bases as universal nucleosides used for oligonucleotide hybridization | Roche Diagnostics GmbH (DE) | 2001-10-04 | — | — | EP | disclosed |
| EP-1138689-A1 | N8- and C8-linked purine bases as universal nucleosides used for oligonucleotide hybridization | Roche Diagnostics GmbH (DE) | 2001-10-04 | — | — | EP | disclosed |