Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TK1 | P04183 | 2/20 | 0.36 |
| ▸ | TK2 | O00142 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27056556 | 0.89 | KDM4E (0.39) | KDM4ETK1TK2POLA1LMNA | |
| SCHEMBL27056553 | 0.81 | KDM4E (0.39) | KDM4EPOLA1LMNATSHR | |
| SCHEMBL27056723 | 0.81 | KDM4E (0.39) | KDM4EPOLA1LMNATSHR | |
| SCHEMBL7782815 | 0.80 | KDM4E (0.41) | KDM4ETK1TK2POLA1LMNA | |
| SCHEMBL7782820 | 0.80 | KDM4E (0.41) | KDM4ETK1TK2POLA1LMNA | |
| SCHEMBL22619624 | 0.78 | GALR3 (0.35) | KDM4ESMN1; SMN2GALR3NR2F2ADRB1 | |
| SCHEMBL22639186 | 0.78 | LMNA (0.38) | KDM4ELMNASMN1; SMN2TSHR | |
| SCHEMBL24420510 | 0.76 | ADRB1 (0.42) | TK1TK2LMNASMN1; SMN2TSHR | |
| SCHEMBL27054425 | 0.76 | ADRB1 (0.42) | TK1TK2LMNASMN1; SMN2TSHR | |
| SCHEMBL14088383 | 0.75 | SMN1; SMN2 (0.39) | LMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829511-B1 | Molecular recognition systems with pyrimidine analog pairing | BENNER STEVEN A (US) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10829511-B1 | Molecular recognition systems with pyrimidine analog pairing | DPYD, DTYMK, TYMS | KDM4E 4089/4885TK1 54/4885TK2 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.