SCHEMBL7782893

SCHEMBL7782893

CCOCn1c(-c2ccc(Cl)cc2)c([S+]([O-])c2ccc(Cl)cc2)c(Br)c1C(F)(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7783602 0.91 NR1H2 (0.30)
SCHEMBL8799002 0.78 MEN1 (0.34) MEN1KMT2A
Chlorfenapyr SCHEMBL40337 0.77 RXFP1 (0.35) MEN1KMT2A
SCHEMBL8664041 0.77 MEN1 (0.32) MEN1KMT2A
SCHEMBL7784780 0.77 PTGS1 (0.37) MEN1KMT2A
SCHEMBL7782978 0.76 KDM4E (0.31)
Chlorfenapyr SCHEMBL28530561 0.76 RXFP1 (0.35) MEN1KMT2A
Chlorfenapyr SCHEMBL27488880 0.76 RXFP1 (0.35) MEN1KMT2A
SCHEMBL8986687 0.76 KMT2A (0.43) MEN1KMT2A
SCHEMBL8986693 0.75 MEN1 (0.38) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0801058-B1 Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents AMERICAN CYANAMID CO (US) 2001-10-10 EP disclosed