Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665381 | 0.79 | EPAS1 (0.35) | PTGS1PTGS2MEN1KMT2ACHRNA7 | |
| SCHEMBL8799002 | 0.78 | MEN1 (0.34) | PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL8986687 | 0.78 | KMT2A (0.43) | PTGS2MAPTMEN1KMT2APTGDR2 | |
| SCHEMBL8986701 | 0.77 | MEN1 (0.42) | PTGS1PTGS2CA9MAPTMEN1 | |
| Chlorfenapyr SCHEMBL40337 | 0.77 | RXFP1 (0.35) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL8664041 | 0.77 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL7786263 | 0.77 | PTGS1 (0.39) | PTGS1PTGS2CA9L3MBTL1MAPT | |
| Chlorfenapyr SCHEMBL28266872 | 0.77 | CA1 (0.41) | PTGS1PTGS2CA9CHRNA7CA1 | |
| SCHEMBL8986708 | 0.77 | MEN1 (0.53) | PTGS1PTGS2MAPTMEN1KMT2A | |
| SCHEMBL7782893 | 0.77 | MEN1 (0.31) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801058-B1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID CO (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5817691-A | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | AMERICAN CYANAMID COMPANY (US) | 1998-10-06 | — | — | US | disclosed |
| EP-0801058-A1 | Arylthio, -sulfinyl and -sulfonyl pyrrole insecticidal agents | American Cyanamid Company (US) | 1997-10-15 | — | — | EP | disclosed |