Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8799268 | 0.89 | MAPK14 (0.32) | — | |
| SCHEMBL9220849 | 0.88 | MAPK14 (0.33) | APOBEC3GPTGS1PTGS2NR1H2NR1H3 | |
| SCHEMBL8797802 | 0.87 | SLC6A3 (0.32) | MEN1KMT2A | |
| SCHEMBL9257392 | 0.84 | MEN1 (0.35) | MEN1KMT2AAPOBEC3G | |
| Chlorfenapyr SCHEMBL40337 | 0.81 | RXFP1 (0.35) | MEN1KMT2A | |
| SCHEMBL8664041 | 0.81 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL8986687 | 0.80 | KMT2A (0.43) | MEN1KMT2APTGS2 | |
| Chlorfenapyr SCHEMBL27488880 | 0.80 | RXFP1 (0.35) | MEN1KMT2A | |
| Chlorfenapyr SCHEMBL28530561 | 0.80 | RXFP1 (0.35) | MEN1KMT2A | |
| SCHEMBL8986701 | 0.79 | MEN1 (0.42) | MEN1KMT2APTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481182-B1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID CO (US) | 1997-01-29 | — | — | EP | claimed |
| US-5157047-A | Miticides | AMERICAN CYANAMID COMPANY (US) | 1992-10-20 | — | — | US | claimed |
| EP-0481182-A1 | Bis- and tris(trifluoromethyl) arylpyrrole insecticidal and acaricidal agents | AMERICAN CYANAMID COMPANY (US) | 1992-04-22 | — | — | EP | claimed |