Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6851419 | 0.98 | ALDH1A1 (0.54) | ALDH1A1GAAPGRPTGS1MAPK1 | |
| SCHEMBL2085785 | 0.83 | ALDH1A1 (0.50) | ALDH1A1GAAPGRPTGS1MAPK1 | |
| SCHEMBL4066419 | 0.81 | ALDH1A1 (0.48) | ALDH1A1GAAPGRPTGS1MAPK1 | |
| SCHEMBL3961756 | 0.81 | ALDH1A1 (0.48) | ALDH1A1GAAPGRPTGS1MAPK1 | |
| SCHEMBL47807 | 0.81 | TDP1 (0.62) | ALDH1A1GAAMAPK1HSD17B10ATM | |
| SCHEMBL30134334 | 0.81 | TDP1 (0.62) | ALDH1A1GAAMAPK1HSD17B10ATM | |
| SCHEMBL27853484 | 0.81 | TDP1 (0.72) | ALDH1A1GAAMAPK1HSD17B10ATM | |
| Bromide SCHEMBL6849870 | 0.80 | ATM (0.54) | ALDH1A1GAAATMTDP1KDM4E | |
| SCHEMBL8207532 | 0.80 | TDP1 (0.54) | ALDH1A1GAAPGRPTGS1MAPK1 | |
| SCHEMBL17923940 | 0.80 | TDP1 (0.57) | ALDH1A1GAAMAPK1HSD17B10ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651034-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2006-05-03 | — | — | EP | claimed |
| WO-2005013687-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2005-02-17 | — | — | WO | claimed |
| EP-1504664-A1 | Organic compounds | Novartis AG (CH) | 2005-02-09 | — | — | EP | claimed |
| CN-118266473-A | Pest control agent composition for agricultural and horticultural applications and method for using the same | 日本农药株式会社 | 2024-07-02 | — | — | CN | disclosed |
| CN-109690404-A | PHOTOSENSITIVE RESIN COMPOSITION AND PHOTOSENSITIVE RESIN LAMINATE | 旭化成株式会社 | 2019-04-26 | — | — | CN | disclosed |
| CN-102349540-B | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG | 2015-07-22 | — | — | CN | disclosed |
| US-8834909-B2 | Granule baits | NOVARTIS AG (CH) | 2014-09-16 | — | — | US | disclosed |
| US-8618162-B2 | Insecticidal carbamates exhibiting species-selective inhibition of acetylcholinesterase (AChE) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2013-12-31 | — | — | US | disclosed |
| CN-101077072-B | Pesticide composition | NOVARTIS AG | 2012-08-08 | — | — | CN | disclosed |
| US-20120122970-A1 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2012-05-17 | — | — | US | disclosed |
| US-8129428-B2 | Insecticidal carbamates exhibiting species-selective inhibition of acetylcholinesterase (AChE) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2012-03-06 | — | — | US | disclosed |
| WO-2005013687-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2005-02-17 | — | — | WO | disclosed |
| EP-1504664-A1 | Organic compounds | Novartis AG (CH) | 2005-02-09 | — | — | EP | disclosed |
| CN-1418126-A | Microcapsule suspensions | BAYER AG (DE) | 2003-05-14 | — | — | CN | disclosed |
| CN-1401234-A | Pesticide composition | NOVARTIS AG (CH) | 2003-03-12 | — | — | CN | disclosed |
| CN-1092488-C | Pesticide composition | NOVARTIS AG (CH) | 2002-10-16 | — | — | CN | disclosed |
| CN-1220578-A | Pesticide composition | NOVARTIS AG (CH) | 1999-06-23 | — | — | CN | disclosed |
| CN-1161690-A | Substituted pyridines, their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1997-10-08 | — | — | CN | disclosed |
| US-4205066-A | Bait compositions for anthropophilic flies | AIRWICK INDUSTRIES, INC. (US) | 1980-05-27 | — | — | US | disclosed |
| US-3938986-A | ISOPROPYL N-PHENYLCARBAMATE OR ISOPROPYL N-(3-CHLOROPHENYL)CARBAMATE AND 4-CHLOROPHENYL N-METHYLCARBAMATE | PPG INDUSTRIES, INC. (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122970-A1 | INSECTICIDAL CARBAMATES EXHIBITING SPECIES-SELECTIVE INHIBITION OF ACETYLCHOLINESTERASE (AChE) | ACHE, BCHE, CHAT | ALDH1A1 960/4885GAA 1339/4885PGR 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.