Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773484 | 0.82 | ALDH1A1 (0.51) | ALDH1A1MAPK1MEN1KMT2AMAPT | |
| SCHEMBL27571004 | 0.81 | L3MBTL1 (0.47) | ALDH1A1MAPK1L3MBTL1MEN1CRHBP | |
| SCHEMBL6136487 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1MEN1CRHBP | |
| SCHEMBL11648038 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPT | |
| SCHEMBL8371983 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPT | |
| SCHEMBL8373359 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPT | |
| SCHEMBL6795518 | 0.80 | MAPT (0.57) | ALDH1A1MAPK1MEN1KMT2ATDP1 | |
| SCHEMBL13619913 | 0.79 | L3MBTL1 (0.42) | ALDH1A1MAPK1L3MBTL1MEN1CRHBP | |
| SCHEMBL11133173 | 0.79 | MAPK1 (0.44) | ALDH1A1MAPK1L3MBTL1MEN1CRHBP | |
| SCHEMBL4316258 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1MEN1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713093-B1 | Improved methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | BAYER AG (US) | 2001-10-10 | — | — | EP | disclosed |
| US-5663044-A | Methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | BAYER CORPORATION (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0713093-A2 | Improved methodology for colorimetrically determining the concentration of white blood cells in a biological fluid | Bayer Corporation (US) | 1996-05-22 | — | — | EP | disclosed |
| EP-0158204-B1 | COMPOSITION AND TEST DEVICE FOR DETERMINING THE PRESENCE OF LEUKOCYTES, CONTAINING A ZWITTERION COUPLING AGENT | MILES INC. (US) | 1989-11-23 | — | — | EP | disclosed |
| EP-0157326-B1 | COMPOSITION AND TEST DEVICE FOR DETERMINING THE PRESENCE OF LEUKOCYTES, ESTERASE AND PROTEASE IN A TEST SAMPLE | MILES INC. (US) | 1989-05-31 | — | — | EP | disclosed |
| US-4657855-A | DIP-AND-READ, UROGENITAL DISORDERS | MILES LABORATORIES, INC. (US) | 1987-04-14 | — | — | US | disclosed |
| US-4637979-A | Composition and test device for determining the presence of leukocytes containing a zwitterion coupling agent | MILES LABORATORIES, INC. (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0158204-A2 | Composition and test device for determining the presence of leukocytes, containing a zwitterion coupling agent | MILES INC. (US) | 1985-10-16 | — | — | EP | disclosed |
| EP-0157326-A2 | Composition and test device for determining the presence of leukocytes, esterase and protease in a test sample | MILES INC. (US) | 1985-10-09 | — | — | EP | disclosed |