SCHEMBL7783028

SCHEMBL7783028

C=CCc1c(CC=C)c(C(=O)O)c(CC=C)c(CC=C)c1C(N)=O

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
GAA P10253 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL176456 0.91 ALDH1A1 (0.35) KDM4ETSHRMAPTHTT
SCHEMBL30331187 0.90 KDM4E (0.32) KDM4EGAATSHRSMN1; SMN2HSD17B10
SCHEMBL8846408 0.89 KDM4E (0.37) KDM4EGAATSHRSMN1; SMN2HSD17B10
SCHEMBL28779595 0.88 KDM4E (0.33) KDM4EGAATSHRSMN1; SMN2HSD17B10
SCHEMBL11590643 0.87 MAPT (0.33) TSHRMAPT
SCHEMBL14722119 0.85 ALDH1A1 (0.33) KDM4ETSHRMAPT
SCHEMBL271102 0.85 KDM4E (0.35) KDM4EGAATSHRSMN1; SMN2HSD17B10
SCHEMBL29458340 0.85 KDM4E (0.35) KDM4EGAATSHRSMN1; SMN2HSD17B10
SCHEMBL3227961 0.84 KDM4E (0.37) KDM4EGAATSHRSMN1; SMN2HSD17B10
SCHEMBL31511090 0.83 KDM4E (0.32) KDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114746499-A Flame retardant polymer composition 科德宝两合公司 2022-07-12 CN disclosed
EP-0872495-B1 FLUORINE-CONTAINING ELASTIC COPOLYMERS, CURABLE COMPOSITION CONTAINING THE SAME AND SEALANT MADE THEREFROM DAIKIN IND LTD (JP) 2001-11-14 EP disclosed
US-6140437-A CURABLE PERFLUOROMETHYL PERFLUOROVINYL ETHER-TETRAFLUOROETHYLENE COPOLYMER FREE RADICALLY POLYMERIZED IN THE PRESENCE OF A SATURATED HYDROCARBYL DIIODIDE; HIGH TEMPERATURE COMPRESSIVE STRENGTH DAIKIN INDUSTRIES LTD. (JP) 2000-10-31 US disclosed
EP-0872495-A1 FLUORINE-CONTAINING ELASTIC COPOLYMERS, CURABLE COMPOSITION CONTAINING THE SAME AND SEALANT MADE THEREFROM DAIKIN INDUSTRIES, LIMITED (JP) 1998-10-21 EP disclosed