Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ADH1B | P00325 | 1/20 | 0.47 |
| ▸ | ADH1C | P00326 | 1/20 | 0.47 |
| ▸ | ADH1A | P07327 | 1/20 | 0.47 |
| ▸ | ADH7 | P40394 | 1/20 | 0.47 |
| ▸ | OXTR | P30559 | 1/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279836 | 0.82 | GAA (0.63) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL888506 | 0.81 | GAA (0.54) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL4854048 | 0.79 | KDM4E (0.51) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL4854061 | 0.79 | KDM4E (0.51) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL245979 | 0.76 | ALDH1A1 (0.49) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL12674819 | 0.76 | KDM4E (0.57) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL14044150 | 0.76 | GAA (0.56) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL888411 | 0.76 | KDM4E (0.56) | KDM4EGAAMAPTL3MBTL1OXTR | |
| SCHEMBL5266363 | 0.76 | ALDH1A1 (0.45) | KDM4EGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL7782632 | 0.75 | KDM4E (0.51) | KDM4EGAAMAPTL3MBTL1OXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556684-B1 | Process for the preparation of 2-chloro-5-alkylamino-methylpyridines | BAYER AG (DE) | 1996-05-22 | — | — | EP | claimed |
| US-5382671-A | Process for the preparation of 2-chloro-5-alkylaminomethyl-pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-17 | — | — | US | claimed |
| EP-0556684-A1 | Process for the preparation of 2-chloro-5-alkylamino-methylpyridines | BAYER AG (DE) | 1993-08-25 | — | — | EP | claimed |
| EP-0691331-B1 | Process for the preparation of n-acylated 2-chloro-5-aminomethyl-pyridines | BAYER AG (DE) | 2001-10-10 | — | — | EP | disclosed |
| CN-1042934-C | Process for preparing 2-chloro-5-alkylaminomethylpyridines | BAYER AG (DE) | 1999-04-14 | — | — | CN | disclosed |
| US-5580983-A | Process for the preparation of N-acylated 2-chloro-5-aminomethylpyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-03 | — | — | US | disclosed |
| EP-0556684-B1 | Process for the preparation of 2-chloro-5-alkylamino-methylpyridines | BAYER AG (DE) | 1996-05-22 | — | — | EP | disclosed |
| EP-0691331-A1 | Process for the preparation of n-acylated 2-chloro-5-aminomethyl-pyridines | BAYER AG (DE) | 1996-01-10 | — | — | EP | disclosed |
| US-5382671-A | Process for the preparation of 2-chloro-5-alkylaminomethyl-pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-17 | — | — | US | disclosed |
| US-5382671-A | Process for the preparation of 2-chloro-5-alkylaminomethyl-pyridines | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-17 | — | — | US | disclosed |
| EP-0556684-A1 | Process for the preparation of 2-chloro-5-alkylamino-methylpyridines | BAYER AG (DE) | 1993-08-25 | — | — | EP | disclosed |
| EP-0556684-A1 | Process for the preparation of 2-chloro-5-alkylamino-methylpyridines | BAYER AG (DE) | 1993-08-25 | — | — | EP | disclosed |