Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4854061 | 1.00 | KDM4E (0.51) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL18685673 | 0.80 | KDM4E (0.45) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL888506 | 0.79 | GAA (0.54) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL7783116 | 0.79 | KDM4E (0.54) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL18884421 | 0.76 | GAA (0.59) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL9279836 | 0.75 | GAA (0.63) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL18567120 | 0.73 | L3MBTL1 (0.42) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL2125695 | 0.72 | KDM4E (0.59) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL29609117 | 0.72 | KDM4E (0.59) | KDM4EGAAL3MBTL1MAPTALDH1A1 | |
| SCHEMBL28000928 | 0.72 | KDM4E (0.59) | KDM4EGAAL3MBTL1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332512-B2 | Halogenated nitrobutadienes for controlling animal pests | BAYER CROPSCIENCE AG (DE) | 2008-02-19 | — | — | US | disclosed |
| US-20050080272-A1 | Halogenated nitrobutadienes for controlling animal pests | BAYER CROPSCIENCE AG (DE) | 2005-04-14 | — | — | US | disclosed |
| EP-1444221-A1 | HALOGENATED NITROBUTADIENES FOR CONTROLLING ANIMAL PESTS | Bayer CropScience AG (DE) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003040129-A1 | HALOGENATED NITROBUTADIENES FOR CONTROLLING ANIMAL PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080272-A1 | Halogenated nitrobutadienes for controlling animal pests | HDHD5, OTUB1, CBR3 | KDM4E 3135/4885GAA 4112/4885L3MBTL1 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.