SCHEMBL7783377

SCHEMBL7783377

COc1cc(F)c(C=NN=Cc2ccc(F)c(F)c2)c(F)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM5 P08912 2/20 0.47
MAPT P10636 2/20 0.46
CYP1A2 P05177 3/20 0.41
MIF P14174 1/20 0.40
PLA2G7 Q13093 2/20 0.39
NQO2 P16083 1/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
RRM1 P23921 1/20 0.38
NFE2L2 Q16236 2/20 0.38
AMY1A P0DUB6 1/20 0.38
GRIN2D O15399 2/20 0.37
GRIN3B O60391 2/20 0.37
GRIN1 Q05586 2/20 0.37
GRIN2A Q12879 2/20 0.37
GRIN2B Q13224 2/20 0.37
GRIN2C Q14957 2/20 0.37
GRIN3A Q8TCU5 2/20 0.37
TAAR1 Q96RJ0 1/20 0.37
TRPA1 O75762 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7783373 1.00 CHRM5 (0.47) CHRM5MAPTCYP1A2MIFPLA2G7
SCHEMBL7791876 0.87 GRIN2D (0.50) CHRM5CYP1A2MIFNQO2CYP1A1
SCHEMBL7791872 0.87 GRIN2D (0.50) CHRM5CYP1A2MIFNQO2CYP1A1
SCHEMBL7793636 0.86 CHRM5 (0.42) CHRM5MAPTCYP1A2NQO2CYP1A1
SCHEMBL7793635 0.86 CHRM5 (0.42) CHRM5MAPTCYP1A2NQO2CYP1A1
SCHEMBL7788406 0.86 NQO2 (0.51) CHRM5MAPTCYP1A2NQO2CYP1A1
SCHEMBL7788411 0.86 NQO2 (0.51) CHRM5MAPTCYP1A2NQO2CYP1A1
SCHEMBL7791406 0.85 MAPT (0.56) CHRM5MAPTCYP1A2MIFRRM1
SCHEMBL7791404 0.85 MAPT (0.56) CHRM5MAPTCYP1A2MIFRRM1
SCHEMBL7789040 0.84 NPC1 (0.53) CHRM5MAPTCYP1A2NQO2CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825176-B1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK & CHEMICALS (JP) 2001-11-14 EP disclosed
US-6010642-A LIGHT SCATTERING LIQUID CRYSTAL DISPLAY DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-01-04 US disclosed
EP-0825176-A1 Azine derivative, process for the preparation thereof, nematic liquid crystal composition and liquid crystal display system comprising same DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-02-25 EP disclosed