SCHEMBL7783476

SCHEMBL7783476

FC(F)C(F)(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.33
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7782743 1.00 LMNA (0.40) LMNATHRBCA2
SCHEMBL5692333 0.97 LMNA (0.38) LMNATHRB
SCHEMBL9720186 0.93 LMNA (0.40) LMNATHRBCA2
SCHEMBL9720164 0.93 LMNA (0.40) LMNATHRBCA2
SCHEMBL2041303 0.90 LMNA (0.38) LMNATHRB
SCHEMBL2042607 0.90 LMNA (0.38) LMNATHRB
SCHEMBL1270589 0.87 LMNA (0.33) LMNA
SCHEMBL1271594 0.86 LMNA (0.30) LMNA
SCHEMBL11415815 0.81 LMNA (0.30) LMNA
SCHEMBL1272303 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825167-B1 COMPOUNDS AND SURFACTANTS ASAHI DENKA KOGYO KK (JP) 2001-10-04 EP disclosed
US-5929290-A A HYDROPHILIC POLYETHER HAVING A FLUORO-SUBSTITUTED ALKYL END GROUP AND A (METH)ALLYL GLYCIDYL END GROUP; EMULSIFIERS AND DISPERSANTS FOR EMULSION AND SUSPENSION POLYMERIZATION, RESP.; RESIN REFORMING AGENTS; ANTISOILANTS FOR POLYESTERS ASAHI DENKA KOGYO K. K. (JP) 1999-07-27 US disclosed
EP-0825167-A1 COMPOUNDS AND SURFACTANTS ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1998-02-25 EP disclosed