Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720164 | 1.00 | LMNA (0.40) | LMNATHRBCA2 | |
| SCHEMBL7782743 | 0.93 | LMNA (0.40) | LMNATHRBCA2 | |
| SCHEMBL7783476 | 0.93 | LMNA (0.40) | LMNATHRBCA2 | |
| SCHEMBL2041303 | 0.90 | LMNA (0.38) | LMNATHRB | |
| SCHEMBL5692333 | 0.90 | LMNA (0.38) | LMNATHRB | |
| SCHEMBL2042607 | 0.90 | LMNA (0.38) | LMNATHRB | |
| SCHEMBL1270589 | 0.87 | LMNA (0.33) | LMNA | |
| SCHEMBL11415815 | 0.81 | LMNA (0.30) | LMNA | |
| SCHEMBL1271594 | 0.79 | LMNA (0.30) | LMNA | |
| SCHEMBL1272303 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104503-A | Radiation in presence of group 2b metal | YALE UNIVERSITY (US) | 1992-04-14 | — | — | US | disclosed |