Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336996 | 0.82 | MEN1 (0.54) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL14783716 | 0.82 | MEN1 (0.54) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL9731633 | 0.79 | WDR5 (0.65) | WDR5MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7782156 | 0.79 | WDR5 (1.00) | WDR5LMNASMN1; SMN2PRSS1KDM4E | |
| Hydrochloric Acid SCHEMBL3663564 | 0.77 | WDR5 (0.63) | WDR5MEN1KMT2AALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL30382158 | 0.77 | WDR5 (0.63) | WDR5MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3368887 | 0.77 | WDR5 (0.66) | WDR5LMNAPRSS1 | |
| SCHEMBL1221676 | 0.77 | WDR5 (0.64) | WDR5MEN1KMT2AALDH1A1PRSS1 | |
| SCHEMBL1431527 | 0.76 | LMNA (0.64) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL2718074 | 0.75 | MEN1 (0.54) | MEN1KMT2AALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1142881-A1 | POLY(ADP-RIBOSE) POLYMERASE INHIBITORS CONSISTING OF PYRIMIDINE DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |