Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455106 | 0.75 | LMNA (0.36) | LMNAMAPK1CES2CES1 | |
| SCHEMBL28431328 | 0.66 | — | — | |
| SCHEMBL28891517 | 0.61 | — | — | |
| SCHEMBL8775519 | 0.61 | — | — | |
| SCHEMBL10435053 | 0.60 | LMNA (0.40) | LMNAMAPK1HPGDCES2CES1 | |
| SCHEMBL4647750 | 0.58 | — | — | |
| SCHEMBL11431034 | 0.58 | LMNA (0.49) | LMNAMAPK1HPGDCES2CES1 | |
| SCHEMBL18537100 | 0.57 | LMNA (0.47) | LMNAMAPK1HPGDCES2CES1 | |
| SCHEMBL890219 | 0.55 | LMNA (0.65) | LMNAMAPK1HPGDCES2CES1 | |
| SCHEMBL9221845 | 0.55 | LMNA (0.65) | LMNAMAPK1HPGDCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141068-A1 | ISOCYANATE-BASED HARDENABLE PREPARATIONS | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039182-A1 | ISOCYANATE-BASED HARDENABLE PREPARATIONS | BASF AKTIENGESELLSCHAFT (DE) | 2000-07-06 | — | — | WO | disclosed |
| EP-0103323-B1 | PROCESS FOR THE PREPARATION OF STABILIZED POLYISOCYANATES, STABILIZED POLYISOCYANATES HAVING RETARDED REACTIVITY AND THEIR USE IN THE PREPARATION OF POLYURETHANES | BAYER AG (DE) | 1987-12-16 | — | — | EP | disclosed |