SCHEMBL890219

SCHEMBL890219

CC(=O)[C@H](O)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.65
MAPK1 P28482 1/20 0.65
HPGD P15428 1/20 0.63
CES2 O00748 2/20 0.58
CES1 P23141 2/20 0.58
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
SRC P12931 2/20 0.48
CYP2D6 P10635 1/20 0.48
KMT2A Q03164 1/20 0.45
NAAA Q02083 2/20 0.44
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9221845 1.00 LMNA (0.65) LMNAMAPK1HPGDCES2CES1
SCHEMBL26259 1.00 LMNA (0.65) LMNAMAPK1HPGDCES2CES1
SCHEMBL30785017 0.87 PTGS2 (0.57) LMNAMAPK1HPGDCES2CES1
Mandelic Acid SCHEMBL2689157 0.83 LMNA (0.86) LMNAMAPK1HPGDCES2CES1
SCHEMBL11221250 0.82 RXRA (0.51) LMNAMAPK1HPGDCES2CES1
SCHEMBL27619969 0.81 HPGD (0.64) LMNAMAPK1HPGDCES2CES1
Mandelic Acid SCHEMBL7279536 0.80 LMNA (0.90) LMNAMAPK1HPGDCES2CES1
Mandelic Acid SCHEMBL5313046 0.79 LMNA (1.00) LMNAMAPK1HPGDCES2CES1
SCHEMBL4882534 0.79 LMNA (0.56) LMNAMAPK1HPGDCES2CES1
Mandelic Acid SCHEMBL165161 0.79 LMNA (1.00) LMNAMAPK1HPGDCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113784945-A Process for preparing R-phenylacetylcarbinol and beta-aminoalcohols 马拉迪制药有限公司 2021-12-10 CN claimed
CN-107075495-B Lyase, DNA encoding the lyase, vector comprising the DNA, and method for asymmetric synthesis of (S) -phenylacetylcarbinol 于利奇研究中心有限公司 2021-10-29 CN claimed
CN-108387652-B Method for detecting impurities in compound paracetamol diphenhydramine tablets 四川省食品药品检验检测院 2021-03-02 CN claimed
EP-3160937-B1 A NOVEL METHOD FOR SYNTHESIS OF OPTICALLY PURE BETA-AMINO ALCOHOLS EMBIO LTD (IN) 2020-12-30 EP claimed
WO-2019246488-A9 COMPOSITIONS AND METHODS FOR THE PRODUCTION OF PYRUVIC ACID AND RELATED PRODUCTS USING DYNAMIC METABOLIC CONTROL DUKE UNIVERSITY (US) 2020-10-29 WO claimed
EP-3160937-A1 A NOVEL METHOD FOR SYNTHESIS OF OPTICALLY PURE BETA-AMINO ALCOHOLS Embio Limited (IN) 2017-05-03 EP claimed
US-20170101654-A1 ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE CHIRAL AMINES EMBIO LIMITED (IN) 2017-04-13 US claimed
EP-2558585-B1 A recombinant process for the production of R-aromatic alpha-hydroxy ketones INDIAN INST TECHNOLOGY BOMBAY (IN) 2016-02-17 EP claimed
WO-2015198108-A1 A NOVEL METHOD FOR SYNTHESIS OF OPTICALLY PURE BETA-AMINO ALCOHOLS EMBIO LIMITED (IN) 2015-12-30 WO claimed
EP-2744908-A1 ENZYMATIC SYNTHESIS OF OPTICALLY ACTIVE CHIRAL AMINES Embio Limited (IN) 2014-06-25 EP claimed
EP-1240347-A4 YEAST-BASED PROCESS FOR PRODUCTION OF L-PAC UNIV VICTORIA (AU) 2003-04-16 EP claimed
WO-2003020942-A2 PROCESS FOR PRODUCTION OF R-PHENYLACETYLCARBINOL BY AN ENZYMATIC PROCESS IN A TWO-PHASE SYSTEM BASF AKTIENGESELLSCHAFT (DE) 2003-03-13 WO claimed
EP-1240347-A1 YEAST-BASED PROCESS FOR PRODUCTION OF L-PAC VICTORIA UNIVERSITY OF TECHNOLOGY (AU) 2002-09-18 EP claimed
EP-1142864-A1 PROCESS FOR PRODUCING L-ERYTHRO-(1R,2S)-2-AMINO-1-PHENYLPROPAN-1-OL NAGASE & COMPANY, LTD. (JP) 2001-10-10 EP claimed
WO-2001044486-A1 YEAST-BASED PROCESS FOR PRODUCTION OF L-PAC VICTORIA UNIVERSITY OF TECHNOLOGY (AU) 2001-06-21 WO claimed
US-6004789-A ISOLATING GENE FROM A PRODUCER ORGANISM AND REPLACING CODON FOR TRYPTOPHAN AT POSITION 1174-1176 TO AN AMINO ACID WITH REDUCED VOLUME RATIO; FOR ENZYME WHICH PRODUCES MAINLY (R)-(-)-PHENYLACETYL CARBINOL; FOR MANUFACTURE OF EPHEDRINE FORSCHUNGSZENTRUM JULICH GMBH (DE) 1999-12-21 US claimed
WO-1999063103-A1 YEAST-BASED PROCESS FOR PRODUCTION OF L-PAC VICTORIA UNIVERSITY OF TECHNOLOGY (AU) 1999-12-09 WO claimed
CN-1192244-A Process for obtaining acyloins, pyruvate decarboxylases suitable therefor and their production and DNA sequences of the PDC gene coding them FORSCHUNGSZENTRUM JUELICH GMBH (DE) 1998-09-02 CN claimed
EP-0828841-A2 PROCESS FOR OBTAINING ACYLOINS, PYRUVATE DECARBOXYLASES SUITABLE THEREFOR AND THEIR PRODUCTION AND DNA SEQUENCES OF THE PDC GENE CODING THEM FORSCHUNGSZENTRUM JÜLICH GMBH (DE) 1998-03-18 EP claimed
WO-1996037620-A2 PROCESS FOR OBTAINING ACYLOINS, PYRUVATE DECARBOXYLASES SUITABLE THEREFOR AND THEIR PRODUCTION AND DNA SEQUENCES OF THE PDC GENE CODING THEM Forschungszentrum Jülich GmbH (DE) 1996-11-28 WO claimed