SCHEMBL778356

SCHEMBL778356

C=Cc1ccc(OP(=O)(Oc2ccc(C=C)cc2)C(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
MAOB P27338 2/20 0.41
MAOA P21397 1/20 0.41
MMP13 P45452 1/20 0.40
ALDH1A1 P00352 4/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 1/20 0.38
TAS1R3 Q7RTX0 2/20 0.38
TAS1R1 Q7RTX1 2/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 1/20 0.37
PKM P14618 2/20 0.36
HTT P42858 2/20 0.36
ATM Q13315 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
HPGD P15428 1/20 0.36
NLRP1 Q9C000 1/20 0.36
GAA P10253 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777303 0.87 CYP3A4 (0.55) CYP3A4TSHRMMP13ALDH1A1LMNA
SCHEMBL778425 0.82 ALDH1A1 (0.44) CYP3A4TSHRMAOBMMP13ALDH1A1
SCHEMBL777534 0.80 MEN1 (0.50) CYP3A4TSHRALDH1A1LMNANPC1
SCHEMBL779808 0.78 CYP2C19 (0.51) CYP3A4TSHRMAOBALDH1A1LMNA
SCHEMBL778003 0.77 NPC1 (0.40) CYP3A4ALDH1A1LMNAMAPTNPC1
SCHEMBL4900360 0.77 ALDH1A1 (0.67) MAOBMAOAALDH1A1LMNAMAPT
SCHEMBL13079826 0.75 KMT2A (0.58) MAOBMAOAALDH1A1LMNAMAPT
SCHEMBL3887080 0.75 TSHR (0.48) CYP3A4TSHRALDH1A1LMNAMAPT
SCHEMBL8016262 0.75 KMT2A (0.58) MAOBMAOAALDH1A1LMNAMAPT
SCHEMBL463760 0.73 TDP1 (0.52) MAOBMAOAALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed