SCHEMBL8016262

SCHEMBL8016262

C=Cc1ccc(OC(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 11/20 0.58
PRSS1 P07477 1/20 0.55
ACR P10323 1/20 0.55
MAPT P10636 2/20 0.51
GFER P55789 1/20 0.51
MEN1 O00255 2/20 0.49
LMNA P02545 2/20 0.47
TDP1 Q9NUW8 1/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPK1 P28482 1/20 0.47
GBA1 P04062 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
RAB9A P51151 2/20 0.46
ALDH1A1 P00352 2/20 0.46
NPC1 O15118 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
MAOA P21397 1/20 0.45
MAOB P27338 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13079826 1.00 KMT2A (0.58) KMT2APRSS1ACRMAPTGFER
SCHEMBL103296 0.91 KMT2A (0.54) KMT2APRSS1MAPTGFERMEN1
SCHEMBL16812851 0.91 KMT2A (0.54) KMT2APRSS1MAPTGFERMEN1
SCHEMBL24086181 0.90 MAPT (0.55) KMT2APRSS1ACRMAPTGFER
SCHEMBL12637603 0.88 KMT2A (0.50) KMT2APRSS1ACRMAPTGFER
SCHEMBL1088940 0.87 KMT2A (0.51) KMT2AMAPTGFERMEN1LMNA
SCHEMBL1088035 0.87 KMT2A (0.51) KMT2AMAPTGFERMEN1LMNA
SCHEMBL28924617 0.87 MAPT (0.68) KMT2APRSS1ACRMAPTGFER
SCHEMBL3132842 0.87 MAPT (0.68) KMT2APRSS1ACRMAPTGFER
SCHEMBL13607266 0.87 MAPT (0.68) KMT2APRSS1ACRMAPTGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2189477-B1 Radiation curable compositions for food applications AGFA GRAPHICS NV (BE) 2017-07-19 EP disclosed
US-20070037894-A1 Multifunctional menomers and polyarylene compsotions therefrom HAHNFELD JERRY L 2007-02-15 US disclosed
US-20070037894-A1 Multifunctional menomers and polyarylene compsotions therefrom HAHNFELD JERRY L 2007-02-15 US disclosed
US-6111133-A Process for preparing substituted styrenes LUCENT TECHNOLOGIES INC. (US) 2000-08-29 US disclosed
EP-0589621-B1 Substituted styrenes AT & T CORP (US) 1998-06-03 EP disclosed
EP-0589621-A1 Substituted styrenes AT&T Corp. (US) 1994-03-30 EP disclosed