Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786261 | 0.78 | SLC6A2 (0.36) | CYP2D6SLC6A2SLC6A4GAASLC6A3 | |
| SCHEMBL5698914 | 0.77 | HTR2C (0.50) | PNMTCHRNB2CHRNA4HTR2CGAA | |
| SCHEMBL1498947 | 0.77 | HTR2C (0.50) | PNMTCHRNB2CHRNA4HTR2CGAA | |
| SCHEMBL16829403 | 0.76 | CTSS (0.44) | GAACTSSKMT2A | |
| SCHEMBL7786361 | 0.76 | CYP19A1 (0.49) | GAA | |
| SCHEMBL7783854 | 0.76 | HPGD (0.36) | CYP2D6SLC6A2SLC6A4HTR2CHTR2B | |
| SCHEMBL7786242 | 0.75 | ACHE (0.38) | CYP2D6HTR2CHTR2BTDP1MEN1 | |
| SCHEMBL7779150 | 0.75 | MEN1 (0.35) | HTR2CHTR2BHTR2AMEN1KMT2A | |
| SCHEMBL2781463 | 0.74 | HTR2C (0.65) | SLC6A2SLC6A4CHRNB2CHRNA4HTR2C | |
| SCHEMBL1409454 | 0.71 | SLC6A2 (0.37) | SLC6A2SLC6A4GAACTSSRBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735142-B1 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5717116-A | TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE | SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0735142-A2 | Process for producing (R)-styrene oxides | SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |