SCHEMBL7784002

SCHEMBL7784002

CCC1(C)C(=O)Oc2cc(C(C)C)ccc21

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.35
GFER P55789 1/20 0.35
HSD17B10 Q99714 1/20 0.35
RNASEH1 O60930 1/20 0.33
PTPN1 P18031 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
ATM Q13315 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7785584 0.88 HPGD (0.34) HPGDGFERHSD17B10RNASEH1PTPN1
SCHEMBL7787072 0.86 RORA (0.34) HPGDGFERHSD17B10
SCHEMBL7783605 0.81 HPGD (0.39) HPGDGFERHSD17B10RNASEH1PTPN1
SCHEMBL7784016 0.80 CNR1 (0.33) MEN1KMT2A
SCHEMBL17368385 0.71 HPGD (0.39) HPGDGFERHSD17B10RNASEH1PTPN1
SCHEMBL2707193 0.68 HSD17B10 (0.33) HPGDGFERHSD17B10MEN1KMT2A
SCHEMBL7783614 0.68 CNR1 (0.34) MEN1KMT2A
SCHEMBL13070864 0.67 TSHR (0.33) MEN1KMT2AATMPDK2
SCHEMBL23621454 0.67 GRIA4 (0.31) HPGDGFERHSD17B10PDK2
SCHEMBL23958979 0.66 HPGD (0.32) HPGDGFERHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707575-B1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH & CIE (CH) 2001-10-24 EP disclosed
US-5679634-A Use of dihydrobenzofuranones as perfuming ingredients FIRMENICH S.A. (CH) 1997-10-21 US disclosed
EP-0707575-A1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH SA (CH) 1996-04-24 EP disclosed
WO-1995030667-A1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH S.A. (CH) 1995-11-16 WO disclosed