SCHEMBL7785584

SCHEMBL7785584

CCCC1(C)C(=O)Oc2cc(C(C)C)ccc21

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.34
GFER P55789 1/20 0.34
HSD17B10 Q99714 1/20 0.34
RNASEH1 O60930 1/20 0.31
PTPN1 P18031 1/20 0.31
RORA P35398 1/20 0.30
RORC P51449 1/20 0.30
RORB Q92753 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7787072 0.92 RORA (0.34) HPGDGFERHSD17B10RORARORC
SCHEMBL7784002 0.88 HPGD (0.35) HPGDGFERHSD17B10RNASEH1PTPN1
SCHEMBL7783614 0.81 CNR1 (0.34)
SCHEMBL7783605 0.79 HPGD (0.39) HPGDGFERHSD17B10RNASEH1PTPN1
SCHEMBL7785829 0.72 PPARG (0.38)
SCHEMBL17368385 0.69 HPGD (0.39) HPGDGFERHSD17B10RNASEH1PTPN1
SCHEMBL7784016 0.68 CNR1 (0.33)
SCHEMBL2707193 0.66 HSD17B10 (0.33) HPGDGFERHSD17B10
SCHEMBL13070864 0.65 TSHR (0.33)
SCHEMBL23621454 0.65 GRIA4 (0.31) HPGDGFERHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0707575-B1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH & CIE (CH) 2001-10-24 EP disclosed
EP-0707575-A1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH SA (CH) 1996-04-24 EP disclosed
WO-1995030667-A1 USE OF DIHYDROBENZOFURANONES AS SCENTING INGREDIENTS FIRMENICH S.A. (CH) 1995-11-16 WO disclosed