SCHEMBL7784133

SCHEMBL7784133

CO[C@@H]1[C@H](O)[C@@H](O)[C@H](c2ccc3c(O)c(C(C)=NOCCn4cncn4)c(=O)oc3c2C)O[C@]1(C)CO

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7792730 0.87 LMNA (0.32)
SCHEMBL7792715 0.86 KMT2A (0.33)
SCHEMBL7784156 0.86 PDGFRB (0.30)
SCHEMBL7605603 0.85 LMNA (0.33)
SCHEMBL7784152 0.80 LMNA (0.35)
SCHEMBL7608589 0.80 LMNA (0.36)
SCHEMBL6942331 0.78 LMNA (0.37)
SCHEMBL7612818 0.76 ALDH1A1 (0.43)
SCHEMBL8381251 0.76 KDM4E (0.39)
SCHEMBL7793432 0.76 HSP90AA1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906326-B1 NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE AVENTIS PHARMA SA (FR) 2001-11-21 EP disclosed