Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7793432 | 0.92 | HSP90AA1 (0.32) | HSP90AA1HSP90AB1 | |
| SCHEMBL7605603 | 0.86 | LMNA (0.33) | HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL7793409 | 0.86 | HSP90AA1 (0.33) | HSP90AA1HSP90AB1KDM4EALDH1A1HPGD | |
| SCHEMBL6866195 | 0.81 | HSP90AB1 (0.52) | HSP90AA1HSP90AB1KDM4EALDH1A1HPGD | |
| SCHEMBL6866197 | 0.81 | HSP90AB1 (0.52) | HSP90AA1HSP90AB1KDM4EALDH1A1HPGD | |
| SCHEMBL7784158 | 0.80 | ALDH1A1 (0.45) | HSP90AA1HSP90AB1KDM4EALDH1A1HPGD | |
| SCHEMBL7792730 | 0.79 | LMNA (0.32) | HSP90AA1HSP90AB1 | |
| SCHEMBL7793422 | 0.78 | KDM4E (0.35) | HSP90AA1HSP90AB1KDM4EALDH1A1HPGD | |
| SCHEMBL7608589 | 0.78 | LMNA (0.36) | HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL7784152 | 0.76 | LMNA (0.35) | HSP90AA1HSP90AB1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906326-B1 | NOVEL AROMATIC DERIVATIVES SUBSTITUTED BY A RIBOSE, THEIR METHOD OF PREPARATION AND APPLICATION AS MEDICINE | AVENTIS PHARMA SA (FR) | 2001-11-21 | — | — | EP | disclosed |