SCHEMBL7784167

SCHEMBL7784167

CCCCCCCc1c(CCC)cccc1Oc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 1/20 0.50
LTB4R2 Q9NPC1 1/20 0.50
PPARA Q07869 2/20 0.46
LTA4H P09960 2/20 0.45
HRH1 P35367 1/20 0.45
ALOX5 P09917 1/20 0.44
PTGS2 P35354 1/20 0.44
RIPK1 Q13546 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
PPARG P37231 1/20 0.44
THRA P10827 1/20 0.42
THRB P10828 1/20 0.42
POLB P06746 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL587821 0.95 PPARA (0.50) LTB4RLTB4R2PPARALTA4HHRH1
SCHEMBL4629233 0.95 PPARA (0.50) LTB4RLTB4R2PPARALTA4HHRH1
SCHEMBL5576826 0.95 PPARA (0.50) LTB4RLTB4R2PPARALTA4HHRH1
SCHEMBL6679277 0.94 PPARA (0.49) LTB4RLTB4R2PPARALTA4HHRH1
SCHEMBL11811179 0.94 PPARA (0.49) LTB4RLTB4R2PPARALTA4HHRH1
SCHEMBL2468938 0.94 ALOX5 (0.50) LTB4RLTB4R2PPARALTA4HHRH1
SCHEMBL28405999 0.89 HRH1 (0.49) LTB4RLTB4R2PPARALTA4HHRH1
SCHEMBL407448 0.84 HRH1 (0.59) PPARALTA4HHRH1ALOX5PTGS2
SCHEMBL20895821 0.84 HRH1 (0.59) PPARALTA4HHRH1ALOX5PTGS2
SCHEMBL8016071 0.84 HRH1 (0.59) PPARALTA4HHRH1ALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0803548-B1 Colored thermoplastic resin composition ORIENT CHEMICAL IND (JP) 2001-10-24 EP disclosed
EP-0803548-A2 Colored thermoplastic resin composition ORIENT CHEMICAL INDUSTRIES, LTD. (JP) 1997-10-29 EP disclosed