SCHEMBL6679277

SCHEMBL6679277

CCCCCCCCCCCCc1cccc(Oc2ccccc2)c1CCCCCCCCCCCC.[NaH]

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.49
ALOX5 P09917 1/20 0.48
PTGS2 P35354 1/20 0.48
LTB4R Q15722 1/20 0.47
LTB4R2 Q9NPC1 1/20 0.47
PPARG P37231 1/20 0.47
LTA4H P09960 2/20 0.45
HRH1 P35367 1/20 0.45
LIPG Q9Y5X9 1/20 0.45
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
RIPK1 Q13546 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
BID P55957 1/20 0.42
BCL2L1 Q07817 1/20 0.42
MCL1 Q07820 1/20 0.42
BAK1 Q16611 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11811179 1.00 PPARA (0.49) PPARAALOX5PTGS2LTB4RLTB4R2
SCHEMBL5576826 0.98 PPARA (0.50) PPARAALOX5PTGS2LTB4RLTB4R2
SCHEMBL4629233 0.98 PPARA (0.50) PPARAALOX5PTGS2LTB4RLTB4R2
SCHEMBL587821 0.98 PPARA (0.50) PPARAALOX5PTGS2LTB4RLTB4R2
SCHEMBL2468938 0.97 ALOX5 (0.50) PPARAALOX5PTGS2LTB4RLTB4R2
SCHEMBL7784167 0.94 LTB4R (0.50) PPARAALOX5PTGS2LTB4RLTB4R2
SCHEMBL28405999 0.92 HRH1 (0.49) PPARAALOX5PTGS2LTB4RLTB4R2
SCHEMBL7897926 0.89 HRH1 (0.57) PPARAALOX5PTGS2PPARGLTA4H
SCHEMBL11884064 0.89 HRH1 (0.57) PPARAALOX5PTGS2PPARGLTA4H
SCHEMBL21351755 0.89 HRH1 (0.57) PPARAALOX5PTGS2PPARGLTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0998520-B1 PVC MIXTURE AND METHOD FOR ITS PRODUCTION NORSK HYDRO AS (NO) 2004-11-17 EP disclosed
US-6441085-B1 MIXING A DISPERSION OF SPHERICAL AND COMPACT POLYVINYL CHLORIDE (PVC)PARTICLES WITH A NARROW SIZE DISTRIBUTION (CV 0-25%) IN THE RANGE 10 TO 50 MICROMETERS WITH PVC LATEX, PROCESSING THE FORMED DISPERSION INTO FREE-FLOWING DRY NORSK HYDRO ASA (NO) 2002-08-27 US disclosed
US-6176908-B1 MIXTURE OF RED AND MAGENTA PIGMENT, POLYMERIC DISPERSANT AND FLUORESCENT DYE E. I. DU PONT DE NEMOURS AND COMPANY 2001-01-23 US disclosed
EP-0998520-A1 PVC MIXTURE AND METHOD FOR ITS PRODUCTION NORSK HYDRO ASA (NO) 2000-05-10 EP disclosed
WO-1999003912-A1 PVC MIXTURE AND METHOD FOR ITS PRODUCTION NORSK HYDRO ASA (NO) 1999-01-28 WO disclosed