Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | MAOA | P21397 | 2/20 | 0.63 |
| ▸ | MAOB | P27338 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22289694 | 0.87 | RAB9A (0.79) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7782979 | 0.85 | MAPT (0.70) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7597335 | 0.85 | MAPT (0.73) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10977880 | 0.84 | GAA (0.83) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL14612489 | 0.83 | RAB9A (0.77) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8803541 | 0.82 | LTA4H (0.79) | ALDH1A1SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL7566619 | 0.82 | MAPT (0.81) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL7784349 | 0.82 | GAA (0.54) | ALDH1A1SMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL14096629 | 0.81 | RAB9A (0.69) | MAPTALDH1A1RAB9ALMNAALOX12 | |
| SCHEMBL10977876 | 0.81 | GAA (0.83) | ALDH1A1SMN1; SMN2RAB9ANPC1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137633-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1137647-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034268-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000034237-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |