SCHEMBL7784420

SCHEMBL7784420

C=C(C)C(=O)Nc1cccc(S(=O)(=O)NS(=O)(=O)c2ccc(OC)cc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.53
MAPT P10636 6/20 0.52
SMN1; SMN2 Q16637 6/20 0.52
HSD17B10 Q99714 1/20 0.52
CYP19A1 P11511 1/20 0.51
GAA P10253 1/20 0.49
TCF4 P15884 1/20 0.49
CTNNB1 P35222 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
LMNA P02545 4/20 0.48
ALDH1A1 P00352 3/20 0.48
HTT P42858 4/20 0.47
POLB P06746 1/20 0.47
RAB9A P51151 2/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
NR2F2 P24468 1/20 0.46
MAPK1 P28482 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11842413 0.87 TDP1 (0.56) MAPTSMN1; SMN2TDP1LMNAALDH1A1
SCHEMBL27404350 0.82 TDP1 (0.56) ATMMAPTSMN1; SMN2GAATDP1
SCHEMBL393893 0.79 TDP1 (0.59) MAPTSMN1; SMN2GAATDP1LMNA
SCHEMBL27404207 0.78 TDP1 (0.51) MAPTSMN1; SMN2GAATDP1LMNA
SCHEMBL7785812 0.78 IDO1 (0.51) MAPTHSD17B10GAALMNAALDH1A1
SCHEMBL7597973 0.78 TDP1 (0.64) MAPTSMN1; SMN2GAATDP1LMNA
SCHEMBL8472237 0.78 TDP1 (0.64) SMN1; SMN2TDP1ALDH1A1HTTPOLB
SCHEMBL396170 0.77 TDP1 (0.56) ATMMAPTGAATDP1LMNA
SCHEMBL7782556 0.77 LMNA (0.54) ATMMAPTSMN1; SMN2GAALMNA
Anisole SCHEMBL7784425 0.77 TDP1 (0.44) ATMMAPTSMN1; SMN2GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671660-B1 Lead-frame forming material FUJI PHOTO FILM CO LTD (JP) 2001-10-17 EP disclosed
US-5670293-A LIGHT SENSITIVE MATERIAL WITH COPPER OR NICKEL ALLOYS, DRYING A PHOTOSENSITIVE LAYER AND WINDING THE COATED WEB INTO STRIPS AND STACKING FUJI PHOTO FILM CO., LTD. (JP) 1997-09-23 US disclosed
EP-0671660-A2 Lead-frame forming material FUJI PHOTO FILM CO., LTD. (JP) 1995-09-13 EP disclosed