SCHEMBL7782556

SCHEMBL7782556

C=C(C)C(=O)Nc1ccc(S(=O)(=O)NS(=O)(=O)c2ccc3ccccc3c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
ALDH1A1 P00352 3/20 0.54
GAA P10253 2/20 0.54
PLA2G7 Q13093 3/20 0.51
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
KDM4E B2RXH2 2/20 0.50
MAPT P10636 2/20 0.50
CA2 P00918 1/20 0.50
GLA P06280 1/20 0.50
POLB P06746 1/20 0.50
HPGD P15428 1/20 0.50
MAPK1 P28482 1/20 0.50
ATM Q13315 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
GPR27 Q9NS67 1/20 0.48
HDAC3 O15379 1/20 0.47
HDAC4 P56524 1/20 0.47
HDAC1 Q13547 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL397717 0.90 SMN1; SMN2 (0.61) LMNASMN1; SMN2ALDH1A1GAAPLA2G7
SCHEMBL398954 0.90 SMN1; SMN2 (0.68) LMNASMN1; SMN2ALDH1A1GAAPLA2G7
SCHEMBL7785812 0.86 IDO1 (0.51) LMNAALDH1A1GAAMEN1KMT2A
SCHEMBL67919 0.83 MEN1 (0.61) LMNASMN1; SMN2ALDH1A1GAAMEN1
SCHEMBL7777757 0.81 HTT (0.47) LMNAALDH1A1MEN1KMT2APOLB
SCHEMBL397572 0.81 AKR1C3 (0.59) LMNASMN1; SMN2ALDH1A1GAAPLA2G7
SCHEMBL14607535 0.81 L3MBTL1 (0.57) LMNASMN1; SMN2ALDH1A1GAAMEN1
SCHEMBL7784361 0.81 IDO1 (0.55) LMNASMN1; SMN2ALDH1A1GAAMEN1
SCHEMBL11842413 0.80 TDP1 (0.56) LMNASMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL7784393 0.80 L3MBTL1 (0.49) LMNASMN1; SMN2ALDH1A1GAAPLA2G7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0671660-B1 Lead-frame forming material FUJI PHOTO FILM CO LTD (JP) 2001-10-17 EP disclosed
US-5670293-A LIGHT SENSITIVE MATERIAL WITH COPPER OR NICKEL ALLOYS, DRYING A PHOTOSENSITIVE LAYER AND WINDING THE COATED WEB INTO STRIPS AND STACKING FUJI PHOTO FILM CO., LTD. (JP) 1997-09-23 US disclosed
EP-0671660-A2 Lead-frame forming material FUJI PHOTO FILM CO., LTD. (JP) 1995-09-13 EP disclosed