M-Xylene

M-Xylene

SCHEMBL7784482

COCCOC.Cc1cccc(C)c1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.63
ALDH1A1 P00352 3/20 0.46
CYP2D6 P10635 2/20 0.46
IDO1 P14902 2/20 0.45
MAPK1 P28482 1/20 0.44
NPC1 O15118 1/20 0.43
CASP3 P42574 1/20 0.43
SENP8 Q96LD8 1/20 0.43
SENP7 Q9BQF6 1/20 0.43
SENP6 Q9GZR1 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HTT P42858 1/20 0.43
TAAR1 Q96RJ0 1/20 0.41
MAOB P27338 1/20 0.41
RELA Q04206 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
M-Xylene SCHEMBL4808897 0.93 ACHE (0.55) ACHEALDH1A1CYP2D6IDO1MAPK1
M-Xylene SCHEMBL29016502 0.86 ACHE (0.52) ACHEALDH1A1CYP2D6IDO1MAPK1
M-Xylene SCHEMBL15876050 0.84 ACHE (0.63) ACHEALDH1A1CYP2D6IDO1MAPK1
M-Xylene SCHEMBL27490026 0.83 ACHE (0.80) ACHEALDH1A1CYP2D6IDO1MAPK1
M-Xylene SCHEMBL10862586 0.83
SCHEMBL12463 0.83 ACHE (0.57) ACHEALDH1A1CYP2D6MAPK1CYP1A2
Toluene SCHEMBL4761329 0.81 TSHR (0.61) ACHEMAPK1
SCHEMBL10204841 0.80 TAAR1 (0.59) ACHEALDH1A1CYP2D6IDO1TAAR1
SCHEMBL8299779 0.80 IDO1 (0.56) ACHEALDH1A1CYP2D6IDO1TAAR1
M-Xylene SCHEMBL28189 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0838537-B1 METAL SURFACE TREATMENTS, METHOD FOR TREATING METAL SURFACE, AND SURFACE-TREATED METALLIC MATERIAL NIPPON PAINT CO LTD (JP) 2001-10-17 EP disclosed
EP-0838537-A1 METAL SURFACE TREATMENTS, METHOD FOR TREATING METAL SURFACE, AND SURFACE-TREATED METALLIC MATERIAL NIPPON PAINT CO., LTD. (JP) 1998-04-29 EP disclosed