M-Xylene

M-Xylene

SCHEMBL29016502

COCCO.Cc1cccc(C)c1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.52
ALDH1A1 P00352 2/20 0.41
CYP2D6 P10635 2/20 0.41
IDO1 P14902 2/20 0.39
LMNA P02545 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
MAPK1 P28482 1/20 0.38
NPC1 O15118 1/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
HTT P42858 1/20 0.38
DHPS P49366 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
M-Xylene SCHEMBL7784482 0.86 ACHE (0.63) ACHEALDH1A1CYP2D6IDO1MAPK1
Toluene SCHEMBL306002 0.84 TSHR (0.50) ACHEALDH1A1LMNANPC1MAPT
M-Xylene SCHEMBL7784481 0.84 ACHE (0.60) ACHEALDH1A1CYP2D6IDO1LMNA
P-Xylene SCHEMBL3688331 0.81 GAA (0.43) ACHEALDH1A1LMNANPC1CYP3A4
M-Xylene SCHEMBL246698 0.81 ACHE (0.71) ACHEALDH1A1CYP2D6IDO1LMNA
M-Xylene SCHEMBL14118025 0.80 ACHE (0.44) ACHEALDH1A1CYP2D6IDO1LMNA
M-Xylene SCHEMBL4808897 0.80 ACHE (0.55) ACHEALDH1A1CYP2D6IDO1MAPK1
P-Xylene SCHEMBL8994094 0.79 GAA (0.41) ACHEALDH1A1LMNANPC1CYP3A4
O-Xylene SCHEMBL16163023 0.77 TSHR (0.48) ACHEALDH1A1CYP1A2CYP2C19POLB
M-Xylene SCHEMBL15876050 0.77 ACHE (0.63) ACHEALDH1A1CYP2D6IDO1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116253638-A Method for synthesizing 2, 4-dimethoxy benzoyl chloride and 2, 4-dimethoxy benzoic acid 重庆长风化学工业有限公司 2023-06-13 CN claimed