Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397984 | 0.81 | RAPGEF4 (0.50) | TSHRKDM4ECYP3A4CYP2D6PLA2G1B | |
| Hydrochloric Acid SCHEMBL3395950 | 0.80 | RAPGEF4 (0.49) | SMN1; SMN2TSHRKDM4ECYP3A4CYP2D6 | |
| SCHEMBL643037 | 0.80 | ADRB2 (0.56) | TSHRKDM4ECYP3A4CYP2D6CYP1A2 | |
| SCHEMBL4072520 | 0.80 | ADRB2 (0.56) | TSHRKDM4ECYP3A4CYP2D6CYP1A2 | |
| SCHEMBL21817525 | 0.80 | ADRB2 (0.56) | TSHRKDM4ECYP3A4CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL3693820 | 0.78 | ADRB2 (0.54) | TSHRKDM4ECYP3A4CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL31123024 | 0.78 | ADRB2 (0.54) | TSHRKDM4ECYP3A4CYP2D6CYP1A2 | |
| SCHEMBL30597995 | 0.78 | TSHR (0.57) | SMN1; SMN2TSHRKDM4ECYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL31123025 | 0.78 | ADRB2 (0.54) | TSHRKDM4ECYP3A4CYP2D6CYP1A2 | |
| Hydrochloric Acid SCHEMBL28946539 | 0.78 | ADRB2 (0.54) | TSHRKDM4ECYP3A4CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137633-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034237-A2 | ACETAMIDE AND SUBSTITUTED ACETAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |