Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 17/20 | 0.52 |
| ▸ | MMP3 | P08254 | 11/20 | 0.52 |
| ▸ | MMP1 | P03956 | 4/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663579 | 0.92 | MMP2 (0.62) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8650550 | 0.85 | MMP2 (0.62) | MMP2MMP3 | |
| SCHEMBL8655236 | 0.82 | MMP2 (0.48) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8665733 | 0.82 | MMP2 (0.64) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8665571 | 0.80 | MMP2 (0.80) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8652786 | 0.75 | MMP2 (0.64) | MMP2MMP3 | |
| SCHEMBL6417777 | 0.74 | MMP3 (0.63) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6412003 | 0.73 | MMP2 (0.64) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL6413235 | 0.72 | MMP2 (0.65) | MMP2MMP3MMP1MMP9MMP14 | |
| SCHEMBL8652949 | 0.71 | MMP2 (0.50) | MMP2MMP3MMP1MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6251940-B1 | ADMINISTERING TO THE MAMMAL SUFFERING FROM A DISEASES RESPONSIVE TO INHIBIT MONOCYTE AND/OR MACROPHASE AND/OR LYMPHOCYTE ACTIVATION AND OF LYMPHOCYTE PROLIFERATION AN AMIDE DERIVATIVE | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2001-06-26 | — | — | US | disclosed |