Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 6/20 | 0.37 |
| ▸ | PDE2A | O00408 | 6/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787653 | 0.90 | KMT2A (0.38) | MEN1KMT2APOLBMAPKAPK2TSHR | |
| SCHEMBL7780305 | 0.90 | KMT2A (0.38) | MEN1KMT2APOLBMAPKAPK2TSHR | |
| SCHEMBL7785270 | 0.90 | KMT2A (0.38) | MEN1KMT2APOLBMAPKAPK2TSHR | |
| Hydrochloric Acid SCHEMBL7785515 | 0.85 | CXCR2 (0.43) | MEN1KMT2APOLBCXCR2PDE2A | |
| SCHEMBL7785567 | 0.85 | TDP1 (0.42) | MEN1KMT2APOLBMAPKAPK2ALDH1A1 | |
| SCHEMBL7785532 | 0.84 | KMT2A (0.38) | MEN1KMT2APOLBMAPKAPK2TSHR | |
| SCHEMBL7787592 | 0.84 | KMT2A (0.38) | MEN1KMT2APOLBMAPKAPK2TSHR | |
| SCHEMBL7785094 | 0.84 | MAPKAPK2 (0.35) | MEN1KMT2APOLBCXCR2MAPKAPK2 | |
| SCHEMBL7787598 | 0.83 | MAPKAPK2 (0.43) | MEN1KMT2APOLBMAPKAPK2ALDH1A1 | |
| SCHEMBL7787694 | 0.82 | KMT2A (0.41) | MEN1KMT2APOLBMAPKAPK2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |