Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 10/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 2/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785121 | 0.98 | MAPKAPK2 (0.46) | MAPKAPK2POLBMEN1KMT2AACP3 | |
| SCHEMBL7787745 | 0.96 | MAPKAPK2 (0.41) | MAPKAPK2POLBMEN1KMT2AACP3 | |
| SCHEMBL7787694 | 0.95 | KMT2A (0.41) | MAPKAPK2POLBMEN1KMT2AACP3 | |
| SCHEMBL7784990 | 0.95 | POLB (0.46) | MAPKAPK2POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL7787635 | 0.93 | MEN1 (0.38) | MAPKAPK2POLBMEN1KMT2AACP3 | |
| SCHEMBL7785293 | 0.93 | MAPKAPK2 (0.40) | MAPKAPK2POLBMEN1KMT2AACP3 | |
| SCHEMBL7784926 | 0.93 | KMT2A (0.38) | MAPKAPK2POLBMEN1KMT2AACP3 | |
| SCHEMBL7780349 | 0.93 | MEN1 (0.38) | MAPKAPK2POLBMEN1KMT2ALMNA | |
| SCHEMBL7787853 | 0.93 | KMT2A (0.38) | MAPKAPK2POLBMEN1KMT2AACP3 | |
| SCHEMBL7784925 | 0.93 | ALDH1A1 (0.41) | MAPKAPK2POLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |