Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.36 |
| ▸ | GALR2 | O43603 | 3/20 | 0.35 |
| ▸ | GALR1 | P47211 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787472 | 0.92 | MEN1 (0.40) | MEN1KMT2APOLBACKR3MAPKAPK2 | |
| SCHEMBL7785096 | 0.92 | MEN1 (0.40) | MEN1KMT2APOLBACKR3MAPKAPK2 | |
| SCHEMBL7789190 | 0.86 | ACKR3 (0.41) | MEN1KMT2APOLBACKR3MAPKAPK2 | |
| SCHEMBL7785718 | 0.86 | ACKR3 (0.41) | MEN1KMT2APOLBACKR3MAPKAPK2 | |
| SCHEMBL7787598 | 0.85 | MAPKAPK2 (0.43) | MEN1KMT2APOLBMAPKAPK2ROCK2 | |
| Hydrochloric Acid SCHEMBL7803812 | 0.85 | ACKR3 (0.40) | MEN1KMT2APOLBACKR3MAPKAPK2 | |
| SCHEMBL7785121 | 0.84 | MAPKAPK2 (0.46) | MEN1KMT2APOLBMAPKAPK2ROCK2 | |
| SCHEMBL7784990 | 0.83 | POLB (0.46) | MEN1KMT2APOLBMAPKAPK2PLK1 | |
| SCHEMBL7787745 | 0.82 | MAPKAPK2 (0.41) | MEN1KMT2APOLBMAPKAPK2ALDH1A1 | |
| SCHEMBL7787694 | 0.81 | KMT2A (0.41) | MEN1KMT2APOLBMAPKAPK2PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |